Instrumental neutron activation analysis (INAA) and liquid chromatography (LC) coupled to high resolution mass spectrometry (HRMS) characterisation of sildenafil based products seized on the Italian illegal market

The commerce of illegal and copyright medicinal products on internet is a serious criminal problem.Drugs for erectile dysfunction such as phosphodiesterase type 5 inhibitor are the most commonly counterfeited medicines in Europe.The search of possible toxic chemical substances in seized products is needed.Moreover, the profiling of the material can

read more

Feasibility and Safety of Perioperative Chemotherapy With Fluorouracil Plus Leucovorin, Oxaliplatin, and Docetaxel for Locally Advanced Gastric Cancer Patients in China

BackgroundNeoadjuvant fluorouracil plus leucovorin, oxaliplatin, and docetaxel (FLOT) has shown significant benefits for gastric cancer patients.However, it has not been well accepted in Asian countries.We conducted a prospective study on the safety and feasibility of the FLOT regimen in iphone 13 atlanta Chinese patients.MethodsPatients with adeno

read more

Application of Modelling and Simulation Approaches to Predict Pharmacokinetics of Therapeutic Monoclonal Antibodies in Pediatric Population

Ethical regulations and limited paediatric participants are key challenges that contribute to a median delay of 6 years in paediatric mAb approval.To overcome these barriers, modelling and simulation methodologies have been adopted to design optimized click here paediatric clinical studies and reduce patient burden.The classical modelling approach

read more

PENINGKATAN MINAT DAN KETRAMPILAN BERCERITA WAYANG PADA PEMBELAJARAN BAHASA JAWA DENGAN PENGGUNAAN ALAT PERAGA WAYANG KULIT PADA SISWA KELAS VI SDN PANGONAN 02 TAHUN PELAJARAN 2015/2016

This study started from the condition of students of class VI SDN Pangonan 02 are less interested and less trampilbercerita miracle academy clothing puppet in the Java language, after monitoring found several factors that cause, among the causes of it are, (1) Learning the Java language monotonous (2) Students are less interested the puppet story (

read more

Dietary Inositol Reduces Fearfulness and Avoidance in Laying Hens

Myo-inositol (inositol) affects memory, and the incidence of depression and anxiety in mammals.An experiment was designed to determine if pure inositol (0.16%), or high levels of phytase (3000 FTU/kg) affect the behaviour of fully beaked Lohmann LSL lite hens fed amino acid sufficient (19% crude protein (CP)) and deficient diets (16% CP), from 19 t

read more